Open positions

Postdoctoral position in the Group of Dagmar Woebken

EXPLORING SURVIVAL AND RESUSCITATION MECHANISMS OF DESERT SOIL BACTERIA

The Woebken Group is accepting applications for a Postdoctoral position.

Background:

Microorganisms in drylands have to endure long periods of drought, interrupted by unpredictable and very short periods of rain. Dormancy - an inactive state or a state of reduced metabolic activity - has long been regarded as a prerequisite for desert soil microorganisms to survive such drought periods. However, as dormancy cannot be sustained indefinitely, phases of resuscitation must also play an important role for long-term survival of desert soil microorganisms and thus for maintaining microbial diversity in one of the harshest environments on the planet.

Project:

In this project, we are investigating the desiccation survival mechanisms of soil microorganisms and the molecular mechanisms of resuscitation. This will be achieved by applying genome-resolved metatranscriptomics of desert soil microbial communities, building upon knowledge gained by our recent metagenomic investigation of biological soil crusts from the Negev Desert, Israel. In situ community transcription patterns will be combined with single-cell activity assays, employing a recently developed heavy water-NanoSIMS assay to detect anabolically active cells, and process measurements.

Requirements:

Candidates should had a PhD degree in microbiology or biological sciences. A background in microbial ecology (ideally soil microbial ecology) with experimental or fieldwork experience is necessary. A comprehensive understanding of microbial physiology, along with generating and interpreting meta-genomic or metatranscriptomic data is mandatory. We expect the candidate to be creative and innovative with her/his/their research ideas. Proficiency in spoken and written English is mandatory. Good scientific writing and verbal communication skills are necessary. The ability to work and communication in a team is essential.

For additional details, please see the pdf.

Please enclose the following documents to your application:

• Letter of motivation (1-2 pages)
• Curriculum Vitae
• University certificate(s), including grades
• Two letters of recommendation

Please send your application as a pdf to dagmar.woebken@univie.ac.at with the subject "Postdoc-position Survival and Resuscitation". 

Master's Student in the group of Martin Polz

We are looking for a highly motivated master's student interested in the co-evolutionary interactions of bacteria and their viruses. The master thesis project is taking place in the research group of Prof. Martin Polz at the Department of Microbial Ecology (DoME) at the University of Vienna. The duration of the project is for six-months.

Background:
Due to the immense evolutionary pressure imposed by phages, bacteria have evolved many mechanisms to evade phage infection and killing, for example, well-known CRISPR-Cas and restriction-modification systems. In turn, bacteriophages have developed various strategies to bypass immunity for successful infection. Yet, the diversity of phage evasion strategies and mechanisms of their action remain largely unknown. Therefore, it is essential to study phage-host interactions to understand the ecological dynamics of microbes and for potential application in phage therapy.

Project:
The master thesis project will study candidate counter-defense proteins of Vibrio phages which act as a counterplay against defense mechanisms of marine Vibrio bacteria. The project will include molecular cloning of the bacterial defense systems and viral counter-defense proteins in a laboratory strain of Vibrio, as well as bioinformatics and viral infection experiments.

Requirements:
Candidates should hold a BSc degree in Biology (particular emphasis in microbiology, microbial ecology, molecular biology, or similar). The applicant should have previous laboratory experience, particularly in the fields of microbiology and molecular biology. We are looking for a master's student who is highly motivated, with good communication skills, and ability to work in a large department with numerous labs. Our lab consists mainly of foreign scientists; therefore, candidates should have excellent English writing and oral communication skills.

Please enclose the following documents to your application:
• Letter of intent
• Curriculum Vitae
Please send it to: martin.f.polz@univie.ac.at